CAGRILINTIDE

Description

Cagrilintide is a long-acting, lipidated analog of human amylin, the 37-amino-acid pancreatic hormone co-secreted with insulin. It is classified as a dual amylin and calcitonin receptor agonist (DACRA): the peptide backbone is stabilized against fibrillation, and a C20 fatty-diacid side chain enables albumin binding for an extended half-life. Cagrilintide is one of the most closely studied amylin analogs in the current literature, both alone and in combination with GLP-1 receptor agonists such as semaglutide. It is supplied here for controlled analytical and laboratory investigation of amylin- and calcitonin-receptor signaling.

Research focus

• Amylin receptor (AMY1–3) and calcitonin receptor (CTR) activation
• Long-acting peptide design: lipidation, albumin binding and fibrillation resistance
• Combination studies with GLP-1 / GIP receptor agonists (e.g. Semaglutide, Tirzepatide, Retatrutide)

This Medtruva catalog product is a laboratory research material, not a clinical product. Store and prepare it only according to an appropriate research protocol, and review all available documentation before use.

For laboratory research use only. Not for human consumption, diagnosis, treatment, or veterinary use.