CJC-1295 (No DAC)

Description

CJC-1295 without Drug Affinity Complex (No DAC), also known as Modified GRF (1–29) or Mod GRF 1-29, is a tetra-substituted synthetic analog of the first 29 amino acids of growth hormone-releasing hormone. Four amino acids in the native GHRH(1–29) sequence are replaced (D-Ala2, Gln8, Ala15, Leu27) to protect the peptide against rapid enzymatic cleavage by DPP-IV and other proteases, while retaining the short, pulse-preserving action profile of the parent fragment. Unlike the DAC-conjugated form, it does not bind albumin, making it the preferred reference compound when a short-acting GHRH-receptor agonist is required. It is supplied here for controlled analytical and laboratory investigation of GHRH-receptor signaling.

Research focus

• GHRH-receptor (GHRH-R) binding and activation
• Short-acting versus long-acting GHRH analog pharmacology (No DAC vs DAC; comparison with Sermorelin and Tesamorelin)
• Co-administration models with growth hormone secretagogues such as Ipamorelin

This Medtruva catalog product is a laboratory research material, not a clinical product. Store and prepare it only according to an appropriate research protocol, and review all available documentation before use.

For laboratory research use only. Not for human consumption, diagnosis, treatment, or veterinary use.